Half-life of testosterone cypionate - Oct 16, 2019 ... Test E/C half life? · Testosterone Propionate: 0.8 days · Testosterone Phenylpropionate: 1.5 days · Testosterone Isocaproate: 4.0 days

 
Beginner Testosterone Propionate Cycle. A beginner user taking this ester alone in an 8 week cycle at 100mg every 2 days is a recommended cycle. A maximum beginner cycle of 500mg weekly for a 10 week cycle provides a good introduction for the new steroid user with a balance between results and side effects.. How to wait on skyrim

See, the half-life of Sustanon is slightly longer than Cypionate due to it being various esters of Testosterone all put in one vial. It has Testosterone Decanoate within, meaning the half-life is a bit longer than that of Cyionate. In reality, that doesn’t make a big difference. Testosterone Sustanon vs Cypionate: Which is Better for ...It is insoluble in water, freely soluble in alcohol, chloroform, dioxane, ether, and soluble in vegetable oils. The chemical name for testosterone cypionate is androst-4-en-3-one, 17-(3-cyclopentyl-1-oxopropoxy)-, (17ß)-. Its molecular formula is …6-8 weeks of Nolvadex at 20mg ED, drop the dose to 10mg ED if sides occur. Also how long after my cycle should I wait to start PCT? 4 times the terminal/biological half life of the longest ester of steroid you used. In your case Cypionate which means 14-20 days after your last pin is when you start PCT. Assuming It takes 44 total days for cypionate testosterone to leave the system. So, the cypionate testosterone half-life would be 22 days. If you took 200mg shot how many days would it take to be back below 400 total Testosterone? Anyone ever done testing or have information about the timeline? Testosterone cypionate or ‘Test C’ is a mid to slow-acting ester of injectable testosterone. Similarly to Test E it was designed to provide a steady release of testosterone into the bloodstream once injected into muscle tissue. After injection test levels rise over two weeks, the half-life of test c is stated at around 14 days. Therefore ...However, the increased fluidity of the olive oil solvent in Testosterone Cypionate, alongside its low concentration of Benzoyl Alcohol preservative, makes Cypionate a preferable choice for subcutaneous injections.” — Testosterone Enanthate contains the carboxylic acid ester, enanthoic acid. It has a half-life of approximately 7-9 days Mar 24, 2019 · In fact, it is practically identical in chemical structure to Testosterone Cypionate, which just has an additional carbon atom attached to it making its half-life slightly longer. Until now, Testosterone Cypionate had not been available in the UK, so when guys came across the pond, they had to switch to Testosterone Enanthate. In the mid-1950s, long-acting testosterone esters (enanthate and cypionate) were introduced, and have since been the preferred testosterone formulation thanks to …Testosterone Cypionate half-life is of 8 days as a testosterone booster, the experts suggest it can stay in the body for almost 44 days in which shows more potency than the rest of the ...What Is the Half Life of Testosterone Cypionate You could easily go online and quickly learn that the answer to what is the half-life of testosterone cypionate when injected is …Hypogonadism in men is a deficiency in serum testosterone (T) levels with symptoms secondary and responsive to T replacement [1, ... reliable estimation of half‐life (T 1/2) of this dose was not possible. The apparent T 1/2 (SD) was 239.63 hours (59.93) for 100 mg SC TE and 172.57 hours (34.74) for 200 mg IM TE. Table 2. Summary of steady ...Description Testosterone cypionate is a sterol ester. It is functionally related to a 3-cyclopentylpropionic acid and a testosterone. ChEBI Testosterone cypionate is a …... ( Figure 1a) is characterized by a short half-life (a few hours), being subject to esterification, which leads to a ...Its half life is determined by its use in the body and what the body does to it. ... For years, I been taking 200mg weekly Pfizer Depo-Testosterone Cypionate w/testosterone levels around 1550. & just a couple weeks ago my pharmacy changed to 200mg Hikma Test Cyp. just did a bloodtest 2 days ago & my test dropped to 415.Oct 8, 2023 · Because Testosterone Cypionate has a longer half life than some other testosterone esters, it takes longer to clear the body; therefore any side effects that do develop may take several weeks to subside once Testosterone Cypionate use stops. Proper Administration and Timing. Testosterone Cypionate has a half life of about eight days. With Enanthate attached you get a steroid with a half life of around 8 days, ... In contrast, Testosterone Cypionate is based in olive oil which is more fluid thinner oil which is likely to cause less irritation when injecting compared to Testosterone Enanthate. Those users who have fortunate enough to have access to both these forms will ...It is insoluble in water, freely soluble in alcohol, chloroform, dioxane, ether, and soluble in vegetable oils. The chemical name for testosterone cypionate is androst-4-en-3-one, 17-(3-cyclopentyl-1-oxopropoxy)-, (17ß)-. Its molecular formula is …Chemical Structure and Half Life of Testosterone Cypionate. Testosterone cypionate belongs to androgens, testosterone dissolved in oil with cyclopentylpropionate ether attached through a 17-beta hydroxyl group (17b-hydroxy-androst-4-en-3-one), its half-life in the body is approximately 6-8 days (full life work 15-16 days), chemical formula C8H14O2.For reference, testosterone enanthate has an elimination half-life of 4.5 days and a mean residence time of 8.5 days and requires frequent administration of approximately once per week. [19] Large fluctuations in testosterone levels result with it, with levels initially being elevated and supraphysiological. [19] Testosterone Cypionate: Half-Life: Usually falls within the range of 8-12 days. Duration in System: Given its longer half-life, cypionate stays active in your body for an extended …In the mid-1950s, long-acting testosterone esters (enanthate and cypionate) were introduced, and have since been the preferred testosterone formulation thanks to …Estradiol cypionate ( EC ), sold under the brand name Depo-Estradiol among others, is an estrogen medication which is used in hormone therapy for menopausal symptoms and low estrogen levels in women, in hormone therapy for trans women, and in hormonal birth control for women. [14] [8] [15] [16] It is given by injection into muscle once every 1 ... ... ( Figure 1a) is characterized by a short half-life (a few hours), being subject to esterification, which leads to a ...Oct 16, 2019 ... Test E/C half life? · Testosterone Propionate: 0.8 days · Testosterone Phenylpropionate: 1.5 days · Testosterone Isocaproate: 4.0 daysMay 17, 2023 · Testosterone cypionate (Depo-testosterone) is an injectable drug used to treat hypogonadism in males. Learn about side effects, warnings, dosage, and more. Oct 16, 2019 ... Test E/C half life? · Testosterone Propionate: 0.8 days · Testosterone Phenylpropionate: 1.5 days · Testosterone Isocaproate: 4.0 daysSep 24, 2014 · Testosterone Cypionate (active half-life: 6-7 days) Testosterone cypionate is probably the most popular and widely used form of testosterone. Cypionate is the esters doctors generally recommend for TRT and HRT treatment from doctors. It is desirable because it can be injected once a week as opposed to twice and is a very smooth injection. Dosage Strengths of Testosterone Cypionate Injection. Testosterone Cypionate Injection: 20 mg/mL 5 mL Vial (Grapeseed Oil) 50 mg/mL 5 mL Vial (Grapeseed Oil) ... the shorter the ester, and the more soluble the medication. A small/short will have a shorter half life – a repeating cycle of a medication’s time within the body. The inverse is ...The half-life of testosterone cypionate is relatively long compared to other forms of testosterone. On average, it is approximately 8 days, but it can range from 6 to …Jul 2, 2022 · The main advantage of injectable testosterone cypionate over other forms of TRT is its long half-life, which allows for fewer injections and less fluctuation in hormone levels. However, it is important to note that injectable testosterone cypionate is not without its side effects[ 1 ], which can include acne, hair loss, and irritability. But, their half-life and active life periods are not the same. Likewise, Cypionate is seldom administered via injection. Testosterone Cypionate comes with a higher risk of side effects. This is because it converts to DHT. It can cause man-boobs or gynecomastia due to its propensity to generate estrogen.The half-life of IM testosterone cypionate is approximately eight days, and enanthate is about the same at seven days. Most testosterone, about 90%, is excreted in the urine as glucuronic or …Feb 10, 2023 · 1. Testosterone cypionate. Testosterone cypionate (Depo-Testosterone) is a common type of injectable testosterone. Available as a brand-name and generic product, it’s injected into your buttock muscle every 1 to 4 weeks. You may inject it at home, or a healthcare provider could give it to you. The recommended dose of testosterone cypionate ... "The half-life of testosterone enanthate during absorption phase (t -) was 3.04 h and during elimination phase (t--), it was 111.40 h." This are actuall measurements of test in blood plasma and not just calculations. Test enth and cyp do not have a 10 or more days half life. I mean even wikipedia cites an 8 day half life period for cyp.Cycles of Testosterone Cypionate are built with the goal of bulking, mass gaining or strength gaining. The steroid is versatile so users can stack it with other compounds for cutting. Regardless of the goal, cycles run between 10-14 weeks due to the longer ester and half-life. Stacking Testosterone Cypionate with other steroids and Testosterone ...Oct 8, 2023 · Testosterone Cypionate is another ester of the testosterone hormone and is one of then most widely used esters by bodybuilders and athletes.Test Cyp has a half life of about 10 to 12 days so is a slower release steroid that is usually used in longer cycles of up to 14 weeks. The half-life of testosterone cypionate when injected intramuscularly is approximately eight days. In many tissues the activity of testosterone appears to depend on reduction to dihydrotestosterone, which binds to cytosol receptor proteins. The steroid-receptor complex is transported to the nucleus where it initiates transcription events and ...By finding out, for example, that testosterone enanthate has a variable half-life of between 5 and 10 days making it one of the longer lasting forms of TRT treatment a patient may decide that the fewer injections it requires is a point in its favor over another form of treatment. Knowing the basic characteristics of any form of Low T therapy ...Oct 8, 2023 · Because Testosterone Cypionate has a longer half life than some other testosterone esters, it takes longer to clear the body; therefore any side effects that do develop may take several weeks to subside once Testosterone Cypionate use stops. Proper Administration and Timing. Testosterone Cypionate has a half life of about eight days. Testosterone enanthate and testosterone cypionate have similar pharmacokinetic profiles, duration of action, and therapeutic efficacy, so they are considered clinically equivalent. 473,474 In adults with hypogonadism, the usual starting dose of testosterone enanthate or cypionate is 150 mg to 200 mg IM every 2 weeks.Testosterone decanoate (BAN Tooltip British Approved Name) is an androgen and anabolic steroid and a testosterone ester. It is a component of Sustanon, along with testosterone propionate, testosterone phenylpropionate, and testosterone isocaproate. The medication has not been marketed as a single-drug preparation. Testosterone …The half-life of testosterone cypionate when injected intramuscularly is approximately eight days. In many tissues the activity of testosterone appears to depend on reduction to dihydrotestosterone, which binds to cytosol receptor proteins. The steroid‑receptor complex is transported to the nucleus where it initiates transcription …The half-life of testosterone cypionate when injected intramuscularly is approximately eight days. In many tissues the activity of testosterone appears to depend on reduction to dihydrotestosterone, which binds to cytosol receptor proteins. The steroid-receptor complex is transported to the nucleus where it initiates transcription events and ...The half life of each ester is one of the main differences between them. Cypionate has an approximately 8 day half life, Enanthate and Propionate have a short elimination half life of about 4.5 days. …Testosterone decanoate (BAN Tooltip British Approved Name) is an androgen and anabolic steroid and a testosterone ester. It is a component of Sustanon, along with testosterone propionate, testosterone phenylpropionate, and testosterone isocaproate. The medication has not been marketed as a single-drug preparation. Testosterone …The latest research on DHT Outcomes. Expert analysis on potential benefits, dosage, side effects, and more. Dihydrotestosterone (DHT) is a derivative of testosterone that is known ...There is considerable variation in the half-life of unbound testosterone, ranging from 10 to 100 minutes. ... Whilst the majority of our patients are on Testosterone Cypionate as this is the Gold Standard, some of my patients are fortunate enough to have their testosterone prescribed through the NHS, under my guidance and supervision. ...Mar 24, 2019 · In fact, it is practically identical in chemical structure to Testosterone Cypionate, which just has an additional carbon atom attached to it making its half-life slightly longer. Until now, Testosterone Cypionate had not been available in the UK, so when guys came across the pond, they had to switch to Testosterone Enanthate. Here at Lifehacker, we are endlessly inundated with tips for how to live a more optimized life—but not all tips are created equal. The best ones are the ones that stick; here are t...The half-life of testosterone cypionate when injected intramuscularly is approximately eight days. In many tissues the activity of testosterone appears to depend on reduction to dihydrotestosterone, which binds to cytosol receptor proteins. The steroid-receptor complex is transported to the nucleus where it initiates transcription events and ...Unmodified testosterone has a half-life of 10 minutes; to overcome this limitation, testosterone is esterified and then dissolved in oil to allow for sustained release into the circulation after injection. ... Studies involving SC administration of testosterone cypionate or enanthate have used 1-mL Luer-Lok syringes with a 20- or 25-gauge 5/8 ...Female deer rarely grow antlers, unless they have extremely high testosterone levels, and are typically much smaller than their male counterparts. Male deer do have antlers and are...Pine Pollen is most often used for Pine Pollen refers to the pollen of trees in the pinus genera, which are sometimes used as dietary supplements. Scots Pine (Pinus sylvestris) con...Testosterone cypionate injection, USP is available in two strengths, 100 mg/mL and 200 mg/mL testosterone cypionate. There is a lack of substantial evidence that androgens are effective in fractures, surgery, convalescence, and functional uterine bleeding. The half-life of testosterone cypionate when injected intramuscularly is approximately ...Testosterone Cypionate: Half-Life: Usually falls within the range of 8-12 days. Duration in System: Given its longer half-life, cypionate stays active in your body for an extended …Oct 26, 2021 · In a study of weekly SC testosterone enanthate or testosterone cypionate (50-150 mg) in 63 transgender men, 20 participants achieved goal serum total testosterone concentrations (348-1197 ng/dL) with 50 mg/week, 34 with 75 to 80 mg/week, 7 with 100 mg/week, and 2 with 150 mg/week . Here at Lifehacker, we are endlessly inundated with tips for how to live a more optimized life—but not all tips are created equal. The best ones are the ones that stick; here are t...The goals of TRT are to restore serum testosterone levels to within the mid-normal physiological range associated with the patient’s age group, generally considered …Testosterone cypionate: Depo-Testosterone: Oil solution: 50–250 mg 1x/1–4 weeks Testosterone isobutyrate: Agovirin Depot: Aqueous suspension: 50–100 mg 1x/1–2 weeks Testosterone phenylacetate b: Perandren, Androject: Oil solution: 50–200 mg 1x/3–5 weeks Mixed testosterone esters: Sustanon 100, Sustanon 250: Oil solution: 50–250 mg ... Apr 29, 2021 · Explanation of Cypionate Ester. As said earlier, Testosterone Cypionate half life is long and that’s because of the Cypionate attached ester to the testosterone hormone. Testosterone Cypionate half life is 12-14 days. As a comparison, Testosterone Propionate half life is 1-3 days and as much as you can notice, the difference is huge. Chemical Structure and Half Life of Testosterone Cypionate. Testosterone cypionate belongs to androgens, testosterone dissolved in oil with cyclopentylpropionate ether attached through a 17-beta hydroxyl group (17b-hydroxy-androst-4-en-3-one), its half-life in the body is approximately 6-8 days (full life work 15-16 days), chemical formula C8H14O2.May 14, 2023 · The half-life of a drug is the amount of time it takes for half of the drug to be eliminated from the body. Testosterone cypionate has a half-life of around 8 days, while testosterone enanthate has a slightly longer half-life of around 10.5 days. This means that testosterone enanthate stays in the body slightly longer than testosterone cypionate. Mar 24, 2019 · In fact, it is practically identical in chemical structure to Testosterone Cypionate, which just has an additional carbon atom attached to it making its half-life slightly longer. Until now, Testosterone Cypionate had not been available in the UK, so when guys came across the pond, they had to switch to Testosterone Enanthate. It persists in the body for a longer time. It has a shorter active life and persists in the body for a short time. Has a half-life of 12 days. Has a half-life of 10.5 days. Testosterone Cypionate has less testosterone per milligram. Testosterone Enanthate has more testosterone per milligram. One carbon atom heavier.Testosterone enanthate is a prodrug of testosterone and is an androgen and anabolic–androgenic steroid (AAS). That is, it is an agonist of the androgen receptor (AR). Pharmacokinetics. Testosterone enanthate has an elimination half-life of 4.5 days and a mean residence time of 8.5 days when used as a depot intramuscular injection.Pharmacodynamics. Testosterone antagonizes the androgen receptor to induce gene expression that causes the growth and development of masculine sex organs and secondary sexual characteristics. 5,14,15,16,17,18,19,20 The duration of action of testosterone is variable from patient to patient with a half life of 10-100 minutes. …This is because suspension’s detection time is 1-2 days, with a half-life of less than 24 hours. However, testosterone propionate, for example, can be detected for up to 2 weeks, and thus you wouldn’t be able to use this closer to the competition (if being tested). ... Testosterone enanthate and cypionate are similar esters in many respects ...Injectable testosterone therapy used in humans is commonly in the form of either testosterone cypionate, enanthate, and undecanoate. In this experiment, we utilized testosterone propionate, re-constituted in grape seed oil. ... Subcutaneous testosterone pellets have a terminal half-life of approximately 70.8 days, with an apparent mean ...Keep in mind that Testosterone Cypionate dosage is ranged between 200 mg and 1000 mg per week but the dosage highly depends on your ultimate goals. ... Due to long half life of the compound, all weekly dosage might be used once per week, but most people use it twice per week to maintain stable blood levels. For example, if you plan 200 …Consumption of Testosterone may improve the quality of life, but at the same time, its uncontrolled usage will lead to some harmful side-effects. Testosterone Enanthate doesn’t last long, whereas Testosterone Cypionate lasts longer. Testosterone Cypionate has a half-life of 12 days whereas it is 10-11 days for Testosterone Enanthate.With Testosterone Enanthate we see a very similar pattern, even with IM injections, though there is a slightly higher difference between the peak and trough due to a small half-life variation with Testosterone Enanthate and Testosterone Cypionate: Figure 14 – Approximate average daily release of Testosterone at 12.5mg of TE every dayWelcome back to Mid-Week Meditations, Lifehacker’s weekly dip into the pool of stoic wisdom, and a guide to using its waters to reflect on and improve your life. Welcome back to Mi...As Testosterone Cypionate possesses a half-life of around 10 – 12 days, it is recommended that Testosterone Cypionate is administered once per week at an …The chemical name for Testosterone Cypionate, USP is androst-4-en-3-one,17- (3-cyclopentyl-1-oxopropoxy)-, (17β)-. Its molecular formula is C H O, and the molecular weight 412.61. Testosterone Cypionate Injection, USP is available in one strength, 200 mg/mL Testosterone Cypionate, USP. Endogenous androgens are responsible for normal growth and ... Pharmacodynamics. Testosterone antagonizes the androgen receptor to induce gene expression that causes the growth and development of masculine sex organs and secondary sexual characteristics. 5,14,15,16,17,18,19,20 The duration of action of testosterone is variable from patient to patient with a half life of 10-100 minutes. …July 13, 2023. Testosterone Cypionate 200mg. In today's digital age, the convenience of online shopping has extended its reach to even the realm of performance-enhancing substances. With the rise ...The goals of TRT are to restore serum testosterone levels to within the mid-normal physiological range associated with the patient’s age group, generally considered …Testosterone Undecanoate: 750 mg (3 mL) IM injection followed by 750 mg (3 mL) injected after 4 weeks, then 750 mg (3 mL) every 10 weeks thereafter. Testosterone Enanthate and Cypionate: 50 to 400 mg IM injection every 2 to 4 weeks. IMPLANT: 2 to 6 pellets (75 mg each) implanted subcutaneously every 3 to 6 months.Dosage Strengths of Testosterone Cypionate Injection. Testosterone Cypionate Injection: 20 mg/mL 5 mL Vial (Grapeseed Oil) 50 mg/mL 5 mL Vial (Grapeseed Oil) ... the shorter the ester, and the more soluble the medication. A small/short will have a shorter half life – a repeating cycle of a medication’s time within the body. The inverse is ...The people of 4chan are the latest, but were not the first and will probably not be the last, to try to boost their testosterone by drinking raw onion juice. This is a terrible, ho...Testosterone Enanthate is the most popular ester variant of the testosterone steroid. It has a half life of about 8 to 10 days and is a slow release testosterone steroid used in injectable form either for performance enhancement or as a TRT. ... What you’ll need is 1x10ml (250mg/ml) bottle of Testosterone Enanthate or Testosterone …Popular testosterone supplements, testosterone cypionate, propionate and enanthate have traditionally been injected through Intramuscular means as this was previously seen as the only possible method for providing patients with the testosterone esters. ... Your physician is unlikely to be trained on TRT management as the half life of …Testosterone Cypionate half-life: 10 – 12 days. Optimal injection frequency: twice per week, each injection split evenly between each other (for example, Monday and Thursday). Testosterone Suspension half-life: 4 – 24 hours. Optimal injection frequency: once per day (multiple times per day is even better).A day after, it will 250. Then 125, and so on. The half-life of the two testosterone molecules varies, with the Enanthate having a half-life of 4-5 days while the Cypionate has a half-life of 4.5 days. The cypionate ester is heavier, so expect it to disperse slightly slower than Enanthate.... ( Figure 1a) is characterized by a short half-life (a few hours), being subject to esterification, which leads to a ...Testosterone Enanthate is a natural male steroid and can be used safely with Testosterone Cypionate, cypionate testosterone half-life enanthate vs. Both are safe with each other. The only important consideration is always that you don't take in more than about 100mg of testosterone enanthate a day, testosterone enanthate ucinky.I did some fancy-ish integral calculus. The greatest area-under-the-curve occurs very close to the ⅓rd-of-the-half-life. We typically treat the active half-life for cypionate as 14 days and the terminal half-life as 5 days. You want to use terminal half-life. So... Inject Cyp every 40 hours. Enanthate every 36. Decanoate every 3 days ...Testosterone enanthate and testosterone cypionate have similar pharmacokinetic profiles, duration of action, and therapeutic efficacy, so they are considered clinically equivalent. 473,474 In adults with hypogonadism, the usual starting dose of testosterone enanthate or cypionate is 150 mg to 200 mg IM every 2 weeks.

Case: A 33 year old gentleman presented with significantly raised testosterone levels, testicular pain, erectile dysfunction and weight loss.. Blastoise art

half-life of testosterone cypionate

Testosterone is the primary male sex hormone, and its main function is to control male physical features. This hormone is created in the testes, and testosterone helps transform a ...The half-life of testosterone cypionate when injected intramuscularly is approximately eight days. In many tissues the activity of testosterone appears to depend on reduction to dihydrotestosterone, which binds to cytosol receptor proteins. The steroid-receptor complex is transported to the nucleus where it initiates transcription events and ...Apr 20, 2017 · Test cyp's half life is 7-8 days. To reach a steady state of any medication, it takes 5 half lives. Which would be 35-40 days for test cyp. And when you reach a steady state of a medication, you are absolutely correct in regards to the initial dosing being double the amount in your system when a steady state is achieved. The half-life of testosterone cypionate when injected intramuscularly is approximately eight days. In many tissues the activity of testosterone appears to depend on reduction to dihydrotestosterone, which binds to cytosol receptor proteins. The steroid-receptor complex is transported to the nucleus where it initiates transcription events and ...Symptoms of low testosterone levels in men include depression, fatigue, weakness and the loss of sex drive, according to WebMD. Testosterone levels usually begin to decline after a...Get factual answers to questions including what is the half-life of testosterone cypionate injections from doctors who provide adults with Low T therapy. MEDICAL HISTORY FORM 1-213-262-0000 Female deer rarely grow antlers, unless they have extremely high testosterone levels, and are typically much smaller than their male counterparts. Male deer do have antlers and are...Testosterone Cypionate possesses a half-life of approximately 12 days. Therefore, Testosterone Cypionate dosages require administration only twice weekly, with each injection spaced evenly apart. For example, if an …Jul 19, 2023 · The chemical name for testosterone cypionate is androst-4-en-3-one,17- (3-cyclopentyl-1-oxopropoxy)-, (17β)-. Its molecular formula is C 27 H 40 O 3, and the molecular weight 412.61. The structural formula is represented below: Testosterone Cypionate Injection, USP is available as 200 mg/mL testosterone cypionate. Taking testosterone cypionate (Depo-Testosterone) at higher doses than prescribed can lead to misuse. This can cause serious side effects, such as heart attack, …Who Needs Life Insurance? - Who needs life insurance? Usually, those with dependents need life insurance. Find out what factors can determine who needs life insurance. Advertisemen...Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)- cyclopentylpropionate ester. Its benefit compared to other testosterone derivatives is the slow rate of release after injection and longer half-life. It was developed by the company Pharmacia and Upjohn and FDA approved on July 25, 1979. .

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